Alberta AYA Cancer Survivor Study (2021)

Key Features:

• The Alberta Adolescent and Young Adult (AYA) Cancer Survivor Study is the first population-based cohort created to comprehensively assess the risk of late effects in AYA cancer survivors aged 15–39 years at diagnosis in Canada.

• The cohort was formed in collaboration with the Alberta Cancer Registry using data on all AYA first primary malignant neoplasms diagnosed in Alberta between January 1983 and December 2017 (N 1⁄4 24 459). We included a nested clinical cohort to investigate the association between treatment exposures and late effects for individuals diagnosed from 2000 onwards (N 1⁄4 14 372).

• Using deterministic data linkage, subsequent primary cancers and vital status information was obtained for the entire cohort; and 75.5–99.1% of the cohort appeared in the administrative health databases that record hospitalizations, ambulatory care, physician claims, perinatal health and patient-reported outcomes.

• The results from this study will inform clinical care and tertiary prevention strategies seeking to improve physical health, well-being and survivorship care in this population.

• Individuals interested in learning more about the study or seeking research collaborations should visit the study website at [https://ayacancerab.com/].

Diaz, R. L., Moss, S. J., Amin, K. B., Harper, A. S., Henning, J.-W., Logie, N., Schulte, F., McKillop, S., Lang, M., Fidler-Benaoudia, M. M. (2021). Data Resource Profile: The Alberta Adolescent and Young Adult Cancer Survivor Study. International Journal of Epidemiology. doi:10.1093/ije/dyab193